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Capsaicin 8% patch in painful diabetic peripheral neuropathy: a randomized, double-blind, placebocontrolled study

In addition, several molecules have been studied as an adjuvant therapy, including L-carnitine, CoQ 10 , vitamin E, vine tea polyphenol, cytoprotective agents (ursodeoxycholic acid), and insulin sensitizers (pioglitazone and metformin) (94)

In Swiss male albino rats co-supplemented with 7501,000 g/kg/b.w./day AFB1 and 2 mg/0.2 ml olive oil/day, the outcomes showed that curcumin could ameliorate the AFB1-toxic effects in reproduction system of rats by improving caput and cauda epididymis weight and enzymatic activity (422)

TPX2 promotes ferroptosis in LPS-induced C28/I2 chondrocytes via NF-B p65-mediated downregulation of GPX4 and SLC7A11